> Your link is about folic acid supplements, NOT folate. It does not matter and this show you know little about the folate cycle. DHFR, the enzyme that metabol

> Your link is about folic acid supplements, NOT folate. It does not matter and this show you know little about the folate cycle. DHFR, the enzyme that metabolizes Folic Acid, also bidirectionally converts DHF and THF (folates). https://www.uniprot.org/uniprotkb/P00374/entry https://www.uniprot.org/uniprotkb/P00374/entry https://www.researchgate.net/profile/Jack-Fletcher-3/publication/233889895/figure/fig1/AS:300006520180749@1448538536751/Simplified-schematic-of-the-folic-acid-metabolic-cycle-Folate-receptors-transport.png https://www.researchgate.net/profile/Jack-Fletcher-3/publica... > Folic acid is shelf-stable pro-vitamin that about 60-70% of the population is able to turn into Vitamin B9. That would mean 60 to 70% of the population cannot process folate, not just folic acid. When did you even get this number? > Poor methylators are on a spectrum, from 'not very good methylators' to 'very poor methylators'. I don't really grok biochemistry, No, you do not grok at all well. You know who does? Me.