4 ms·

That link says nicotine, caffeine, alcohol, medicines, and anything that is a food is exempt. That would seem to include capsaicin, along with other stuff like

That link says nicotine, caffeine, alcohol, medicines, and anything that is a food is exempt. That would seem to include capsaicin, along with other stuff like Robitussin and nutmeg that can potentially be hallucinogenic if you megadose them.

voxic11 4y ago
It defines food as: > Any substance which— (a) is ordinarily consumed as food, and (b) does not contain a prohibited ingredient > In this paragraph— “food” includes drink; “prohibited ingredient”, in relation to a substance, means any psychoactive substance— (a) which is not naturally occurring in the substance, and (b) the use of which in or on food is not authorised by an EU instrument. So it sounds like Capsaicin produced naturally in things like hot peppers would be fine. But artificially produced Capsaicin added to food might not be.
- 9wzYQbTYsAIc 4y ago
  Sensation is not perception. To be psychoactive, capsaicin would need to warp your perceptions, rather than solely induce the sensation of burning pain.
  - voxic11 4y ago
    As the original article notes it does appear to have a psychoactive effect beyond the sensation of burning pain (though if a sensation of pleasure is a psychoactive effect why wouldn't a sensation of pain be?). I found additional sources going into the likely pharmacology of this effect: > Namely, capsaicin and vanillin (and anandamide itself) are all agonists of the TRPV1 receptor, which stimulates production and release of endogenous anandamide. When mixed with N-linoleoylethanolamide and N-oleoylethanolamide from cacao, which inhibit anandamide breakdown, the levels of endogenous anandamide are augmented further. When breakdown of anandamide is inhibited pharmacologically or genetically, anandamide is able to produce a state of intoxication similar to tetrahydrocannabinol in rodents and nonhuman primates https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706955/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706955/
    - 9wzYQbTYsAIc 4y ago
      Interesting, that does remind me of times that some people would experience a brief “glow” feeling after consuming a handful of “inferno” chicken wings.
- deleted 4y ago
  [deleted]
- lazide 4y ago
  Wait, so psychedelic mushrooms aren’t a drug by that definition?
  - mtlmtlmtlmtl 4y ago
    Psychedelic shrooms are not ordinarily consumed "as food", though they are eaten. But they taste like ass and often cause nausea. The primary purpose is unambiguously to get high. Also, psilocybin is probably still scheduled explicity from before the law was passed.
- wonderwonder 4y ago
  Does it explicitly exclude alcohol? Seems like alcohol would hit all of these marks
  - AlecSchueler 4y ago
    Yes and nicotine
GuB-42 4y ago
Robitussin (dextromethorphan) is now a prescription in several countries for its abuse potential, like codeine. It is a dissociative hallucinogen that can be abused, but it is generally considered a poor substitute to other substances like ketamine, rarely a first choice. Nutmeg is a deliriant on really high doses, and most deliriants are not controlled substances, though they may be classified as poisons. The reason is that tripping on deliriants is generally considered unpleasant, and enough to turn people off quickly.

voxic11 4y ago

It defines food as: > Any substance which— (a) is ordinarily consumed as food, and (b) does not contain a prohibited ingredient > In this paragraph— “food” includes drink; “prohibited ingredient”, in relation to a substance, means any psychoactive substance— (a) which is not naturally occurring in the substance, and (b) the use of which in or on food is not authorised by an EU instrument. So it sounds like Capsaicin produced naturally in things like hot peppers would be fine. But artificially produced Capsaicin added to food might not be.

9wzYQbTYsAIc 4y ago
Sensation is not perception. To be psychoactive, capsaicin would need to warp your perceptions, rather than solely induce the sensation of burning pain.
- voxic11 4y ago
  As the original article notes it does appear to have a psychoactive effect beyond the sensation of burning pain (though if a sensation of pleasure is a psychoactive effect why wouldn't a sensation of pain be?). I found additional sources going into the likely pharmacology of this effect: > Namely, capsaicin and vanillin (and anandamide itself) are all agonists of the TRPV1 receptor, which stimulates production and release of endogenous anandamide. When mixed with N-linoleoylethanolamide and N-oleoylethanolamide from cacao, which inhibit anandamide breakdown, the levels of endogenous anandamide are augmented further. When breakdown of anandamide is inhibited pharmacologically or genetically, anandamide is able to produce a state of intoxication similar to tetrahydrocannabinol in rodents and nonhuman primates https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706955/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706955/
  - 9wzYQbTYsAIc 4y ago
    Interesting, that does remind me of times that some people would experience a brief “glow” feeling after consuming a handful of “inferno” chicken wings.
deleted 4y ago
[deleted]
lazide 4y ago
Wait, so psychedelic mushrooms aren’t a drug by that definition?
- mtlmtlmtlmtl 4y ago
  Psychedelic shrooms are not ordinarily consumed "as food", though they are eaten. But they taste like ass and often cause nausea. The primary purpose is unambiguously to get high. Also, psilocybin is probably still scheduled explicity from before the law was passed.
wonderwonder 4y ago
Does it explicitly exclude alcohol? Seems like alcohol would hit all of these marks
- AlecSchueler 4y ago
  Yes and nicotine

GuB-42 4y ago

Robitussin (dextromethorphan) is now a prescription in several countries for its abuse potential, like codeine. It is a dissociative hallucinogen that can be abused, but it is generally considered a poor substitute to other substances like ketamine, rarely a first choice. Nutmeg is a deliriant on really high doses, and most deliriants are not controlled substances, though they may be classified as poisons. The reason is that tripping on deliriants is generally considered unpleasant, and enough to turn people off quickly.