5 ms·

"Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries" (https://pubmed.ncbi.nlm.nih.gov/30051870

"Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries" (https://pubmed.ncbi.nlm.nih.gov/30051870/ https://pubmed.ncbi.nlm.nih.gov/30051870/) >Among professionals attending entrepreneurship events, T. gondii-positive individuals were 1.8× more likely to have started their own business compared with other attendees (n = 197). Finally, after synthesizing and combining country-level databases on T. gondii infection from the past 25 years with the Global Entrepreneurship Monitor of entrepreneurial activity, we found that infection prevalence was a consistent, positive predictor of entrepreneurial activity and intentions at the national scale, regardless of whether previously identified economic covariates were included. "The association of latent toxoplasmosis and level of serum testosterone in humans" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994116/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994116/) >Comparison of testosterone concentrations and control groups showed that testosterone concentration in study group was higher than that in control group with statistically significant difference. "Toxoplasma gondii infection enhances testicular steroidogenesis in rats" (https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.12042 https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.12042) >Testosterone, a testicular steroid, is known to reduce fear and enhance sexual attractiveness in males. Here, we show that Toxoplasma gondii infection enhances expression of genes involved in facilitating synthesis of testosterone, resulting in greater testicular testosterone production in male rats.

eloff 4y ago
I can see the headlines now "you won't believe this one weird trick for bigger gains and better performance in bed".
- Silverback_VII 4y ago
  What is the legal framework for a product that infects people with "beneficial" parasites ?
  - hanniabu 4y ago
    Just call it a supplement and you can do anything
  - deleted 4y ago
    [deleted]
  - escapecharacter 4y ago
    As long as it doesn’t affect my essential fluids, I’m game
    - brohee 4y ago
      Maybe read https://en.wikipedia.org/wiki/Parasite_%28Grant_novel%29 https://en.wikipedia.org/wiki/Parasite_%28Grant_novel%29 first...
    - brookst 4y ago
      Just take it with pure rain water and you’ll be fine.
  - gumby 4y ago
    Ever seen “probiotics” for sale at the shops? Or live culture yoghurt?
- marginalia_nu 4y ago
  In a world where people are supplementing with turkesterone... It's an arthropod moulting hormone-analogue. But it's an ecdysteroid. So surely its ergogenic. Sure, why not.
frontman1988 4y ago
2 billion people already have the Toxoplasma gondii in their brains. If it were to affect humanity is some profound way, we would have already linked it to something more substantial than n=197 studies of correlating success in entrepreneurship to the virus.
- enkid 4y ago
  That's not how science works.
- jjallen 4y ago
  This may very well be true. I wish you had posted more of a direct criticism of the study in question other than its small sample size. It may have had a similar control group and could be relevant. It could be that individuals with more of the parasite are more likely to become entrepreneurs still.
- TheBigSalad 4y ago
  Good point. We should stop studying it because we should have known by now.
- ajmurmann 4y ago
  There are other studies that link Toxoplasmosis to increased risk taking. Here one on increased likelihood of getting into car accidents: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117239/#__ffn_sectitle https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117239/#__ffn_s.... It's widely known for many years now. Twenty years ago there was a huge report about it on German public radio. The article I looked references research from the seventies. It's been a strange philosophical point to me that catching a parasite that really wants to be in your cat can alter your personality and unless you are a pregnant woman the medical system ignores it.
  - msrenee 4y ago
    What's the medical system going to do about a parasite that often doesn't cause any symptoms that can pinpoint the particular pathogen? Most healthy people clear the infection without ever knowing anything happened. We don't have any way to undo whatever the parasite did while it was active. It's probably possible to create a vaccine, but the full impact in humans is still being explored and a vaccine for a pathogen that's been with us mostly unnoticed since cats have been with us isn't a high priority. I'd also say decades of research into the effects of T. gondii is explicitly not the medical system ignoring it. It's the medical system being aware of it, but there aren't any great solutions at this point. I'd also like to point out the difference between difficult to define risk-taking behavior in adults vs. miscarriage, blindness, neurological issues, and hydrocephalus among other risks to a fetus.

eloff 4y ago

I can see the headlines now "you won't believe this one weird trick for bigger gains and better performance in bed".

Silverback_VII 4y ago
What is the legal framework for a product that infects people with "beneficial" parasites ?
- hanniabu 4y ago
  Just call it a supplement and you can do anything
- deleted 4y ago
  [deleted]
- escapecharacter 4y ago
  As long as it doesn’t affect my essential fluids, I’m game
  - brohee 4y ago
    Maybe read https://en.wikipedia.org/wiki/Parasite_%28Grant_novel%29 https://en.wikipedia.org/wiki/Parasite_%28Grant_novel%29 first...
  - brookst 4y ago
    Just take it with pure rain water and you’ll be fine.
- gumby 4y ago
  Ever seen “probiotics” for sale at the shops? Or live culture yoghurt?
marginalia_nu 4y ago
In a world where people are supplementing with turkesterone... It's an arthropod moulting hormone-analogue. But it's an ecdysteroid. So surely its ergogenic. Sure, why not.

frontman1988 4y ago

2 billion people already have the Toxoplasma gondii in their brains. If it were to affect humanity is some profound way, we would have already linked it to something more substantial than n=197 studies of correlating success in entrepreneurship to the virus.

enkid 4y ago
That's not how science works.
jjallen 4y ago
This may very well be true. I wish you had posted more of a direct criticism of the study in question other than its small sample size. It may have had a similar control group and could be relevant. It could be that individuals with more of the parasite are more likely to become entrepreneurs still.
TheBigSalad 4y ago
Good point. We should stop studying it because we should have known by now.
ajmurmann 4y ago
There are other studies that link Toxoplasmosis to increased risk taking. Here one on increased likelihood of getting into car accidents: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117239/#__ffn_sectitle https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117239/#__ffn_s.... It's widely known for many years now. Twenty years ago there was a huge report about it on German public radio. The article I looked references research from the seventies. It's been a strange philosophical point to me that catching a parasite that really wants to be in your cat can alter your personality and unless you are a pregnant woman the medical system ignores it.
- msrenee 4y ago
  What's the medical system going to do about a parasite that often doesn't cause any symptoms that can pinpoint the particular pathogen? Most healthy people clear the infection without ever knowing anything happened. We don't have any way to undo whatever the parasite did while it was active. It's probably possible to create a vaccine, but the full impact in humans is still being explored and a vaccine for a pathogen that's been with us mostly unnoticed since cats have been with us isn't a high priority. I'd also say decades of research into the effects of T. gondii is explicitly not the medical system ignoring it. It's the medical system being aware of it, but there aren't any great solutions at this point. I'd also like to point out the difference between difficult to define risk-taking behavior in adults vs. miscarriage, blindness, neurological issues, and hydrocephalus among other risks to a fetus.