This screams of Goodhart’s Law, or gaming the metrics. Once you go around messing with biomarker of some disease (i.e., age) the metrics are no longer indicativ

This screams of Goodhart’s Law, or gaming the metrics. Once you go around messing with biomarker of some disease (i.e., age) the metrics are no longer indicative of the underlying phenomenon. https://en.m.wikipedia.org/wiki/Goodhart%27s_law https://en.m.wikipedia.org/wiki/Goodhart%27s_law