Importantly, Proton also integrates DXVK. I don't know the details too well but I think DXVK is responsible for a large part of Proton's "it just works" and it'

Importantly, Proton also integrates DXVK. I don't know the details too well but I think DXVK is responsible for a large part of Proton's "it just works" and it's a separate project from Wine. You can configure Wine to use DXVK but in Proton everything is preconfigured so you never have to think about them as different components.