One thing I can agree with OP, Weinberg and what’s-his-name’s Hallmarks of Cancer series of papers are emblematic of everything that’s wrong with biology resear

One thing I can agree with OP, Weinberg and what’s-his-name’s Hallmarks of Cancer series of papers are emblematic of everything that’s wrong with biology research and why we haven’t made much actionable progress in recent decades in biology: these reviews invented out of thin air dogmatic rules about cancer as if what they know about it is what’s important (in their first review, the immune system is not even mentioned) and the entire field embraces it as the Bible or something. Then when they update it, they pat themselves in the back acting as if it’s all progress now that they have a better model! By the time the second review came out it became damn clear that the role of the immune system in cancer is probably one of the most important aspects we should focus on, but they didn’t want to look like idiots so they still underplayed it’s importance.