I have 1,000+ hours in ONI. IMO the game is more fun if you use the wiki sparingly, if ever; part of the fun is overcoming whatever sunk you last time. Here's

I have 1,000+ hours in ONI. IMO the game is more fun if you use the wiki sparingly, if ever; part of the fun is overcoming whatever sunk you last time. Here's a few tips: 1) Don't feel pressured to grow fast. I have beat the base game and come pretty close to beating the expansion (stopped only by laziness) with no more than 12 dups. You can get really far on just 3-5. Taking too many dups early is like taking VC money, now you've got an aggressive ramp and a time limit. 2) Don't pick up dup skills too fast. All you really need at the start is a digger and a researcher. 3) Don't do advanced research too fast. Pick & choose what you need. Advanced research uses a lot of water, which you might need for electrolysis (oxygen). 4) Gas stratification is your friend. 5) Most germs die off (slowly) in pure water & pure oxygen. 6) Atmospheric chlorine can interact with stuff in pipes. 7) Rock has a lot of thermal mass if you don't dig it out. 8) Go exploring around the map! Go to the edges and see what you find :)