There is a very large number of problem where it is very easy to just run a few independent instances of Python. Web servers definitely fall into this category,

There is a very large number of problem where it is very easy to just run a few independent instances of Python. Web servers definitely fall into this category, splitting requests between processes is trivial. GIL would be an issue for a task which cannot be parallelized and assuming the problem is performance-critical, I would go with C anyway.