Counterpoint: there are four families of Dopamine receptors https://en.wikipedia.org/wiki/Dopamine_receptor https://en.wikipedia.org/wiki/Dopamine_receptor and

Counterpoint: there are four families of Dopamine receptors https://en.wikipedia.org/wiki/Dopamine_receptor https://en.wikipedia.org/wiki/Dopamine_receptor and 7 families of Serotonin receptors: https://en.wikipedia.org/wiki/5-HT_receptor https://en.wikipedia.org/wiki/5-HT_receptor and many of them have orthogonal effects. When I teach abnormal psychology, I like to ask my students "If Prozac is an SSRI, it increases Serotonin receptor activity. However, LSD is a Sertonin agonist, so it also increases Serotonin receptor activity. Why therefore do Prozac and LSD not give the same experience?"