> The more the dynamic behavior of the profiled system and the real system deviate Maybe. I've never found it a problem, but maybe. When I've added a cache, th

> The more the dynamic behavior of the profiled system and the real system deviate Maybe. I've never found it a problem, but maybe. When I've added a cache, the cache comes with instrumentation for exactly that. > Yes, but by doing this they also tremendously increased the complexity of the project It depends. EG if you don't need to worry too much about cache invalidation, adding caching can be as simple as adding a single function call eg like python's lru_cache. It depends on the use case.