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EDITIED TO ADD: Before taking Zinc get your Serum Zinc and RBC Zinc levels tested. Easy to do in the US if you have some money. Also get your Serum Copper and
by FollowingTheDao 4y ago
EDITIED TO ADD:
Before taking Zinc get your Serum Zinc and RBC Zinc levels tested. Easy to do in the US if you have some money.
Also get your Serum Copper and Ceruloplasmin tested since taking zinc at high dose for a while will lower copper since zinc creates Metallothioneins that capture the copper in the intestine before it can be absorbed.
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Hey, thanks for being curious! Science!
Zinc and Tetrahydrobipoterin:
https://pubmed.ncbi.nlm.nih.gov/31732151/ https://pubmed.ncbi.nlm.nih.gov/31732151/
The Gene GCH1 is central to making Tetrahydrobiopterin and uses zinc as a cofactor.
https://www.uniprot.org/uniprotkb/P30793/entry https://www.uniprot.org/uniprotkb/P30793/entry
The zinc coupling of NOS via GCH1:
https://www.ahajournals.org/cms/asset/2cc8b7a0-a31a-4759-bc8d-da0d1f512dcf/7ff2.jpg https://www.ahajournals.org/cms/asset/2cc8b7a0-a31a-4759-bc8...
Uncoupled NOS makes a lot of superoxides, BAD!:
https://www.liebertpub.com/cms/10.1089/ars.2013.5566/asset/images/medium/figure5.gif https://www.liebertpub.com/cms/10.1089/ars.2013.5566/asset/i...
Here is a diagram of all the enzymes that need Tetrahydroibiopterin (BH4):
https://www.researchgate.net/figure/Metabolic-pathway-of-BH4-dopamine-serotonin-and-tyrosine_fig3_322971717 https://www.researchgate.net/figure/Metabolic-pathway-of-BH4...
NOS2 and the immune system:
https://pubmed.ncbi.nlm.nih.gov/24477906/ https://pubmed.ncbi.nlm.nih.gov/24477906/
https://www.jimmunol.org/content/167/5/3000 https://www.jimmunol.org/content/167/5/3000
COVID and NOS2:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754882/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754882/
Zinc and hypertension:
https://pubmed.ncbi.nlm.nih.gov/32090294/ https://pubmed.ncbi.nlm.nih.gov/32090294/
NOS3 uncoupling and hypertension:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816601/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816601/
NOS1 and psychosis:
https://pubmed.ncbi.nlm.nih.gov/12140778/ https://pubmed.ncbi.nlm.nih.gov/12140778/
Zinc and Diabetes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984028/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984028/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407731/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407731/
And the BIG one, Zinc and Heart Arrhythmia, you know the thing that all these your people are suddenly dying with?
https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spares-no-one https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328074/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328074/
You know, they are avoiding looking at zinc, purposefully, and I feel it is a crime against humanity. Seriously.