I appreciate the input, but did you look at the Ki binding figures for CBD in the paper you linked? ~4000 nanomolar antagonist is not nanomolar unless you're re

I appreciate the input, but did you look at the Ki binding figures for CBD in the paper you linked? ~4000 nanomolar antagonist is not nanomolar unless you're really stretching it. It is so high that there are innumberable unrelated compounds with the same very low affinity. It is true it does act as an atagonist, but it is a vacuous truth applicable to so many things that you wouldn't call CB1 or CB2 antagonist.