3 ms·
> 1) Being able to rapidly sequence the genomes of cancer cells to detect common mutations Only of the cancer cells? How are mutations detected in the 0.4% of
by someweirdperson 4y ago
> 1) Being able to rapidly sequence the genomes of cancer cells to detect common mutations
Only of the cancer cells? How are mutations detected in the 0.4% of the DNA that differs in different human beings? Can't there be non-cancerous changes in the other 99.6% that are present in all cells? Is it just a matter of cost, sequencing both too expensive?
- joshuahedlund 4y agoMy initial guess would be that they would compare cancerous vs non-cancerous cells within the same human being
- doctoring 4y agoThe article mentions: "...sequencing DNA from blood samples and tumour biopsies, to look for mutations that are found in the tumour but not in the blood." This is pretty common for most cancer genotyping tests. (Sometimes they compare tumor with saliva or some other "benign" source, but the principle is the same.)