Not responding with regard to any specific treatment, rather more generally. It’s a mixture of several things: * New/Niche Equipment * Few few commoditized inp

Not responding with regard to any specific treatment, rather more generally. It’s a mixture of several things: * New/Niche Equipment * Few few commoditized inputs (e.g. lentiviral vector) * Labor Intensive * These setups look more like labs than large continuous or batch manufacturing sites * Everything requires GMP * This can mean weeks of training new personnel (even for well known manufactures) * Additional time & resources for FDA approval (safety testing, documentation, validation, This is a good reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363291/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363291/