3 ms·

Mounjaro is amazing. The GLP-1 agonists will change weight loss completely.

• BizarroLand 4y ago
  Doesn't do anything to boost your metabolism though. That is the second half of the magic pill we need. 1st a GLP1 agonist to reduce appetite and improve sugar sensitivity and 2nd something that safely and effectively increases metabolism towards but not exceeding nominal levels. Maybe a growth hormone secretagogue or something that affects the mitochondria to make them less calorically efficient or something.
  • jmpman 4y ago
    Agreed. If you look at the Biggest Loser Study, their metabolism was horrible afterwards. They all ballooned back up. Wish they would have published thyroid test results, as I suspect the participants had wonky thyroids. There’s some diet drug which does ramp the mitochondria up, but it works so well, people cook themselves, and now it’s illegal. I expect I’ll be on Mounjaro either continuously, or for a month or two per year, every year for the rest of my life. With Mounjaro, you can effectively fast for an entire day without much issue. Which reminds me, I haven’t had lunch. However, I expect my metabolism is going down as I remain on Mounjaro, and when I stop, expect I’ll also rocket back up.