It's the difference between: "We will run 10 clinical trials testing the efficacy of this drug in men and 5 clinical trials testing its efficacy in women" and

It's the difference between: "We will run 10 clinical trials testing the efficacy of this drug in men and 5 clinical trials testing its efficacy in women" and "We will run 10 clinical trials testing the efficacy of this drug in men and suggest women take a lower dose"