Driving 1% of the variance is not the same as reducing your brain mass by 1%. Without knowing anything about the brain, Reducing your brain mass by 1% sounds pr

Driving 1% of the variance is not the same as reducing your brain mass by 1%. Without knowing anything about the brain, Reducing your brain mass by 1% sounds pretty crazy to me, and probably has extreme negative effects very far before hitting 100% loss. It’s not absurd to say the negative effects of air pollution on this specific outcome are mostly negligible but still not want air pollution for other reasons. Which is a hypothetical statement of course because we don’t have any data here.