4 ms·
I'm trying to understand. The impact reported by the study seems to compound with higher amounts (I would imagine as liver and kidney throughput is exceeded and
by JetAlone 4y ago
I'm trying to understand. The impact reported by the study seems to compound with higher amounts (I would imagine as liver and kidney throughput is exceeded and the poison hits you more directly).
Standard Control:
GMV WMV
0–1 AU −0.030 −0.020
1–2 AU −0.127 −0.074
2–3 AU −0.223 −0.129
So cumulatively, 0-3 drinks is is GMV: -0.380, WMV: -0.223
What I don't know and can't seem to find with a quick search is the conversion method for IDP standard deviations in brain matter relate to absolute percentages of brain matter (which I assume is not linear?). If your comment is correct, then these numbers correlate to an absolute reduction of 2% of brain matter?
I also see that the third drink seems to do about 50% more standard deviation movement than the former 2 put together.
EDIT: Never mind it's been a while since I took statistics, I remembered that standard deviations _are_ a linear amount. I'd been thinking of percentile placement on a normal distribution.
- JetAlone 4y agoI tried to go a little further since the depression study seemed to be focused on total brain matter. I might make a mistake here, but... Grey matter is about 40% of the brain, white matter is 60%, so if we're talking about absolute matter, we should factor that in. For 0 to 3 drinks: GMV: -0.380 x 0.4 = -0.152 SD WMV: -0.223 x 0.6 = -0.1338 SD Should be sum of 0.2858 standard deviations of total brain matter, or about 2.5% reduction. For 0 to 2 drinks: GMV: -0.157 x 0.4 = -0.0628 SD WMV: -0.094 x 0.6 = -0.0564 SD 0.1192 SD or about 1.05% reduction