I'm not convinced by refutations of #2 that point out that we humans have developed technologies that extend our senses, eg. we can now detect neutrinos, gravit

I'm not convinced by refutations of #2 that point out that we humans have developed technologies that extend our senses, eg. we can now detect neutrinos, gravity waves, microwaves, what-have-you. While these are extensions of the senses we have, we still are evolved to understand an environment that is an infinitely narrow slice of all possible environments in the universe, and Earth life's approach is an infinitely narrow slice of all possible ways of perceiving and surviving an underlying reality that is vastly unknowable. As we look into a Universe (or even look around ourselves here on Earth) with our sense extenders, we are still bound by the limitations of our cognition and perception.