I am not really sure what Ousterhout means when talking "datacenter" but one of the key aspects of TCP networked applications is that it really doesn't matter i

I am not really sure what Ousterhout means when talking "datacenter" but one of the key aspects of TCP networked applications is that it really doesn't matter if they are located in a datacenter, at the edge, in a mobile device, in a Raspberry at home or in your car and, better, they can be more or less moved from one hosting to another. Will this mean that application developers need to work with different network stacks at the same time?