> The F-keys are still widely used people and make sense to be their own key. This depends on your platform. On macOS, almost all keyboard shortcuts are centre

> The F-keys are still widely used people and make sense to be their own key. This depends on your platform. On macOS, almost all keyboard shortcuts are centred around the cmd/apple key next to the spacebar (where alt would be on a non-mac keyboard) and an alphanumeric key. F-keys are hardly used and if they do, you know you're likely dealing with a an app ported from Linux or Windows or which is cross-platform. It's personal preference of course, but I like my shortcuts this way as I just have to thumb the cmd key and press any other key within reach, instead of having to stretch to f-keys (cmd+q vs alt+f4) or use any of the other fingers to use the ctrl key for copy pasting (cmd+c vs ctrl+c). I use the small Apple keyboard as a daily driver on my desktop instead of the full version because it has the exact same layout as the keyboard on my laptop. Which is great as I don't have to built muscle memory for 2 layouts. Of course you are missing dedicated home/end/page keys. But the fn button along with the arrow keys make up for that (also cmd/opt + arrow keys often works better for navigating anyways as they are aware of paragraphs, line endings etc).