Rather than throwing out nonsense like "tens of thousands of options" and "I always come across some critical problem" why don't you describe your requirements

Rather than throwing out nonsense like "tens of thousands of options" and "I always come across some critical problem" why don't you describe your requirements and list some of those "critical problems" that seem to uniquely afflict your work, whatever that is. Your actual question doesn't have an answer. No such thing as an "ultimate" database for the same reason we can't objectively agree on the "ultimate" car or the "ultimate" food, or programming language, or anything else. It always comes down to it depends on the requirements.