Intel has a NUC in that form now. PCI-E style backpane in the case can accepts 11th gen and 12th gen CPU boards and a full size GPU. https://www.intel.com/cont

Intel has a NUC in that form now. PCI-E style backpane in the case can accepts 11th gen and 12th gen CPU boards and a full size GPU. https://www.intel.com/content/www/us/en/products/docs/boards-kits/nuc/mini-pcs/nuc-12-extreme.html https://www.intel.com/content/www/us/en/products/docs/boards... But I guess the CPU is still the hub of PCI-E networks right now.