Autoimmune disorders are usually caused when a hidden genetic susceptibility combines with an environmental trigger to create antibodies that are cross-reactive

Autoimmune disorders are usually caused when a hidden genetic susceptibility combines with an environmental trigger to create antibodies that are cross-reactive with yourself. The greater the chemical diversity in your environment, the more genetic susceptibilities will be triggered. The greater the difference between the modern and historical chemical environments, the less effective evolution will have been at making sure those susceptibilities didn't make it to you. Exposure to thousands of diverse, evolutionary novel, otherwise-harmless chemicals is the worst-case scenario for autoimmunity.