The cited paper does a much clearer job, but the article does make an attempt: > Most people diagnosed with depression are offered an oral antidepressant (in c

The cited paper does a much clearer job, but the article does make an attempt: > Most people diagnosed with depression are offered an oral antidepressant (in combination with psychotherapy) as a first-line treatment option. But _if oral antidepressants don’t help_, or _if the person is at imminent risk of hurting themselves_, there are other, more rapid treatment options: ECT, and more recently ketamine or esketamine. > “ECT is consistently more successful than ketamine” at helping _patients with serious depression_ > “We need to improve public awareness of ECT for _treatment-resistant depression_.” (emphasis mine)