3 ms·

This ties in nicely with the Crohn's cold-chain hypothesis. https://pubmed.ncbi.nlm.nih.gov/32949122/ https://pubmed.ncbi.nlm.nih.gov/32949122/ It gives me ho

• carom 4y ago
  I have very weird food autoimmune issues (sinus headaches from a lot of common stuff). Often when I say something about gluten people will bring up the relatively recent increase in intolerances. Some will point to genetically engineered crops, some to the use of glyphosate. I always thought maybe we had more variety and more awareness now (i.e. 1000 years ago my options would have been limited and I'd just suffer, now I have choice). I saw this same article on NPR a few days ago and it is really cool that it might be a genetic adaptation. I almost never get sick (besides from food) so an overactive immune system would make sense. There is also (sometimes contested) academic research about adherence to a gluten free diet having positive health outcomes for autism, schizophrenia, and bipolar disorder. The mechanism, as I've seen it explained, is that autistic people's bodies treat gluten / casein as an opiate (exorphine is the word they use) which mirrors my experience with sinus headaches (it feels like a withdrawal). Wandering post to say this research is super exciting and there is a ton of crazy stuff around food.
  • ksidudwbw 4y ago
    If you factor in that we ran around with ringworms that emit immunosuppresants to protect themselves...