5 ms·

>It is almost certain this drug was synthesized by a Chinese custom synthesis group (the most typical source for these type of substances at scale) and not by A

by tsol 4y ago

>It is almost certain this drug was synthesized by a Chinese custom synthesis group (the most typical source for these type of substances at scale) and not by Australian clandestine chemists. Most people don't realize this, but you can order a synthesis of just about any (legal) chemical with enough money. People do it for pharmaceutical or nootropic drugs sometimes in group buys. It's trivial if you have enough money to find some vaguely legal analog of a recreational drug, and order a synthesis of it. 2f-dck is a ketamine analog that I believe is still legal and reported to be very similar in effect, and I'd guess 2f-nendck is somewhat similar to that. Not that I'm suggesting anyone should, there are risks and it's not an easy process. It's just interesting how easily accessible it is if you have the right information.

Loic 4y ago
To the point to be annoying. I am running an open database of chemical properties[0], I get nearly every single day Chinese companies proposing me to buy whatever compounds they are producing including non legal ones. Even more stupid, I get phone calls and email asking me if I can source stupidly well known illegal drug for a friend doing some research. Even if this is clear that I am just providing experimental data and no chemicals at all. So yes, you can get chemicals very easily and you have a lot of providers which are not really looking at the legality of the stuff. [0]: https://www.chemeo.com https://www.chemeo.com
- rendall 4y ago
  A friend is looking to do research into any one of the following: Can-D, Chew-Z, skooma (moon sugar ok), Jet or UltraJet, spark, spike, spin or spank, and velocet. They are prepared to pay well. You can reach them here: https://youtu.be/PZqx-lMZHM0 https://youtu.be/PZqx-lMZHM0
  - rendall 4y ago
    In case it isn't clear to some people, these are all nerdy references to fictional drugs in video games and science fiction stories where the drug plays an important role in the story
  - zasdffaa 4y ago
    Howzabout some clarky cat? https://www.youtube.com/watch?v=MIAJemmO-bg https://www.youtube.com/watch?v=MIAJemmO-bg The first 5 minute of this is one of the funniest things I've watched.
    - rendall 4y ago
      This video contains content from LDS, who has blocked it in your country on copyright grounds Weird. Mormons getting salty?
      - zasdffaa 4y ago
        That's a pity. It's from Brass Eye (https://en.wikipedia.org/wiki/Brass_Eye https://en.wikipedia.org/wiki/Brass_Eye), a piss-take on panicky documentaries, it's the drugs one and totally brilliant. And they got a mandrill on it. Most of them are well worth a watch, get them if you can.
        rendall 4y ago
        That's pretty great! I was able to see it through the Daily Motion link. I did not see anything overtly Mormon, however. The LDS copyright block is confusing.
    - rendall 4y ago
      I could not watch the video, but from Urban Dictionary, this is a basis for a brilliant prank: ... there is an elaborate verbal dance that you need to go through with them as they pretend not to know what you are talking about, but perseverance is the key here.
    - bel_marinaio 4y ago
      https://www.dailymotion.com/video/x5b9k3m https://www.dailymotion.com/video/x5b9k3m - Brass Eye S01E02 "Drugs" Worked for me in the US
      - rendall 4y ago
  - Our_Benefactors 4y ago
    Sorry, only Zyme is available these days.
- gilleain 4y ago
  Off topic, but Cheméo is very nice: search by InChIKey, similarity search, the page of results as images. Great work!
  - Loic 4y ago
    Thank you! If you need more functionalities, just let me know.
vintermann 4y ago
Still legal for what purposes? Selling for consumption? I doubt it. When you sell stuff as medicine, food or anything in between, of course it should be on you to prove that it's safe. That's not unreasonable. Neither is it unreasonable to ask, if you sit there with 100kg of some novel molecule custom ordered from a Chinese lab, what you were planning to use it for. And it'd better not be selling it for consumption.
- failrate 4y ago
  They are referred to as "research chemicals", so the implication is that they have been synthesizes for e.g. an experiment or animal trial. This is merely puffery to hide the fact that it is a loophole to get technically not yet illegal variants of drugs.
- tokinonagare 4y ago
LinuxBender 4y ago
Will those labs also synthesize non recreational drugs? I would like to be able to stockpile some ace2 binding drugs. I have the formula and the ingredients but lack the equipment to do it accurately and safely. I keep things around in the event of a full economic crash and would just take risks and apply redneck-science if it came to that but a proper lab would be ideal.
- gpcr1949 4y ago
  They definitely will, this is after all the intended purpose of these firms, and some of the more professional among them are producing cGMP APIs at scale in a completely legitimate context. Although if you have a need for ACE2 inhibitors (not sure which kind of binders you need for which purpose ...) that are marketed and formulated it may be more convenient to just source a large amount of the pharmaceutical product, though I can't comment on the legality of doing that.

by tsol 4y ago

Loic 4y ago

To the point to be annoying. I am running an open database of chemical properties[0], I get nearly every single day Chinese companies proposing me to buy whatever compounds they are producing including non legal ones. Even more stupid, I get phone calls and email asking me if I can source stupidly well known illegal drug for a friend doing some research. Even if this is clear that I am just providing experimental data and no chemicals at all. So yes, you can get chemicals very easily and you have a lot of providers which are not really looking at the legality of the stuff. [0]: https://www.chemeo.com https://www.chemeo.com

rendall 4y ago
A friend is looking to do research into any one of the following: Can-D, Chew-Z, skooma (moon sugar ok), Jet or UltraJet, spark, spike, spin or spank, and velocet. They are prepared to pay well. You can reach them here: https://youtu.be/PZqx-lMZHM0 https://youtu.be/PZqx-lMZHM0
- rendall 4y ago
  In case it isn't clear to some people, these are all nerdy references to fictional drugs in video games and science fiction stories where the drug plays an important role in the story
- zasdffaa 4y ago
  Howzabout some clarky cat? https://www.youtube.com/watch?v=MIAJemmO-bg https://www.youtube.com/watch?v=MIAJemmO-bg The first 5 minute of this is one of the funniest things I've watched.
  - rendall 4y ago
    This video contains content from LDS, who has blocked it in your country on copyright grounds Weird. Mormons getting salty?
    - zasdffaa 4y ago
      That's a pity. It's from Brass Eye (https://en.wikipedia.org/wiki/Brass_Eye https://en.wikipedia.org/wiki/Brass_Eye), a piss-take on panicky documentaries, it's the drugs one and totally brilliant. And they got a mandrill on it. Most of them are well worth a watch, get them if you can.
      - rendall 4y ago
        That's pretty great! I was able to see it through the Daily Motion link. I did not see anything overtly Mormon, however. The LDS copyright block is confusing.
  - rendall 4y ago
    I could not watch the video, but from Urban Dictionary, this is a basis for a brilliant prank: ... there is an elaborate verbal dance that you need to go through with them as they pretend not to know what you are talking about, but perseverance is the key here.
  - bel_marinaio 4y ago
    https://www.dailymotion.com/video/x5b9k3m https://www.dailymotion.com/video/x5b9k3m - Brass Eye S01E02 "Drugs" Worked for me in the US
    - rendall 4y ago
- Our_Benefactors 4y ago
  Sorry, only Zyme is available these days.
gilleain 4y ago
Off topic, but Cheméo is very nice: search by InChIKey, similarity search, the page of results as images. Great work!
- Loic 4y ago
  Thank you! If you need more functionalities, just let me know.

vintermann 4y ago

Still legal for what purposes? Selling for consumption? I doubt it. When you sell stuff as medicine, food or anything in between, of course it should be on you to prove that it's safe. That's not unreasonable. Neither is it unreasonable to ask, if you sit there with 100kg of some novel molecule custom ordered from a Chinese lab, what you were planning to use it for. And it'd better not be selling it for consumption.

failrate 4y ago
They are referred to as "research chemicals", so the implication is that they have been synthesizes for e.g. an experiment or animal trial. This is merely puffery to hide the fact that it is a loophole to get technically not yet illegal variants of drugs.
tokinonagare 4y ago

LinuxBender 4y ago

Will those labs also synthesize non recreational drugs? I would like to be able to stockpile some ace2 binding drugs. I have the formula and the ingredients but lack the equipment to do it accurately and safely. I keep things around in the event of a full economic crash and would just take risks and apply redneck-science if it came to that but a proper lab would be ideal.

gpcr1949 4y ago
They definitely will, this is after all the intended purpose of these firms, and some of the more professional among them are producing cGMP APIs at scale in a completely legitimate context. Although if you have a need for ACE2 inhibitors (not sure which kind of binders you need for which purpose ...) that are marketed and formulated it may be more convenient to just source a large amount of the pharmaceutical product, though I can't comment on the legality of doing that.