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> Electronic health records of 2.4 million people in the UK from January 2020 to April 2021 I don't know when the UK rolled vaccines out en masse, but I'm gues

> Electronic health records of 2.4 million people in the UK from January 2020 to April 2021 I don't know when the UK rolled vaccines out en masse, but I'm guessing that most of these people were not vaccinated when they had COVID. Also, if they're looking at records only through April, that means they would have had to have had COVID weeks/months before then, for the follow-up symptoms to be recorded by April 2021. That would make it even more likely that the people were not vaccinated before infection. My understanding is that people who were vaccinated before infection are at somewhat lower risk of long COVID, so it'd be great to see a large study like this of vaccinated people.

deleted 4y ago
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Jedd 4y ago
Indeed. Unsurprisingly, they did make some notes about this in the study: "We were unable to estimate the effect of vaccination and infection year on long COVID symptoms in our study due to the very short follow-up period among those vaccinated and infected in the year 2022 (median 8 (IQR 4–14) and 12 (7–16) days, respectively) compared to those unvaccinated and infected in the year 2021 (33 (16–77) and 64 (31–90) days, respectively). Furthermore, the majority (81%) of patients vaccinated before infection in our cohort were infected with SARS-CoV-2 within 2 weeks of vaccination, which would be before acquiring immunity from vaccination, thus restricting the validity of our data to assess the effects of vaccination on long COVID." https://www.nature.com/articles/s41591-022-01909-w https://www.nature.com/articles/s41591-022-01909-w > ... it'd be great to see a large study like this of vaccinated people. I, too, am very interested in further research in this area, because it will strongly inform my actions now and for the next couple of years. As noted above though, it's frustrating, but it sounds like it's way too early.
- busymom0 4y ago
  Before omicron, there were studies showing the vax didn’t help with long Covid: https://www.washingtonpost.com/health/2022/05/25/long-covid-vaccines-slight-protection/ https://www.washingtonpost.com/health/2022/05/25/long-covid-... https://www.nature.com/articles/s41591-022-01840-0 https://www.nature.com/articles/s41591-022-01840-0 https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51570 https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51570

deleted 4y ago

[deleted]

Jedd 4y ago

Indeed. Unsurprisingly, they did make some notes about this in the study: "We were unable to estimate the effect of vaccination and infection year on long COVID symptoms in our study due to the very short follow-up period among those vaccinated and infected in the year 2022 (median 8 (IQR 4–14) and 12 (7–16) days, respectively) compared to those unvaccinated and infected in the year 2021 (33 (16–77) and 64 (31–90) days, respectively). Furthermore, the majority (81%) of patients vaccinated before infection in our cohort were infected with SARS-CoV-2 within 2 weeks of vaccination, which would be before acquiring immunity from vaccination, thus restricting the validity of our data to assess the effects of vaccination on long COVID." https://www.nature.com/articles/s41591-022-01909-w https://www.nature.com/articles/s41591-022-01909-w > ... it'd be great to see a large study like this of vaccinated people. I, too, am very interested in further research in this area, because it will strongly inform my actions now and for the next couple of years. As noted above though, it's frustrating, but it sounds like it's way too early.

busymom0 4y ago
Before omicron, there were studies showing the vax didn’t help with long Covid: https://www.washingtonpost.com/health/2022/05/25/long-covid-vaccines-slight-protection/ https://www.washingtonpost.com/health/2022/05/25/long-covid-... https://www.nature.com/articles/s41591-022-01840-0 https://www.nature.com/articles/s41591-022-01840-0 https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51570 https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51570