> a drug inducing powerful stimulant effects in one group, and sedating effects in another I firmly believe this has more to do with dosages than anything else

> a drug inducing powerful stimulant effects in one group, and sedating effects in another I firmly believe this has more to do with dosages than anything else. Sure, give a random person a 10mg Adderall and one might be more sedated or hyperactive. Give them 100mg (almost double therapeutic max), and I guarantee they won't be calm sedated. Sure, everyone has a different threshold that needs to be hit for whatever underlying reasons just like alcohol. One beer might make some feel buzzed, one beer might not do anything. But for an average person (not a chronic alcoholic), I guarantee they'll be fucked-up after 6+ beers.