2 ms·
Genetics is rarely that simple. Take the scenario where Gene X has a mutation that causes a chance to get a disease. Gene Y also increases the likelihood of d
by devmor 4y ago
Genetics is rarely that simple.
Take the scenario where Gene X has a mutation that causes a chance to get a disease.
Gene Y also increases the likelihood of developing this disease, but Gene Z mitigates the effect of Gene Y.
Maybe you also have Gene A, B and C which don't directly effect the disease, but lead to less bioavailability of nutrients that prevent the disease.
Now multiply this by tens of thousands, and maybe you also need to include RNA for some diseases/disorders and it's suddenly not very simple.
- Retric 4y agoNone of which matters unless those mutations are common in the population. Remember they didn’t DNA test a significant percentage of the population’s remains they only found things that where already common. As to your point, suppose you have 100 mutations that are impacted by the Black Death but none are president in more than 0.001% of the population. Does it actually change much if some of those go to 0.002%? No A 99% die off or similar bottlenecks can make huge changes at the population level, but a single 50% die off simply isn’t that impactful.