It is not the same, but not that different either. There is a gap of 150 years and a lot of technological development between the relatively simple Tipu Sultan

It is not the same, but not that different either. There is a gap of 150 years and a lot of technological development between the relatively simple Tipu Sultan bamboo rockets that rained on the British in 1799 and ICBMs that can carry a nuclear warhead across the globe, but it is not really a difference of kind. They are both solid-propellant rockets working on the same principle. It is possible that future genetic and epigenetic manipulation will be much more subtle than whatever we can do today. Or perhaps you are addressing the categories. Well, "health" is, to some degree, socially defined. As is "disease". There were times when homosexuality was classified as a disease. Not that distant times. Alan Turing (in)famously committed suicide because of that. As of now, scientists working in the longevity field are pushing for aging itself to be redefined as a disease. Parents of heavily intellectually disabled kids would probably agree to any reasonably safe treatment that would help their kids, if such treatment existed. Not having enough general intelligence is a big obstacle in everyday life. HN gets an audience of mostly smart people; most of them cannot even begin to understand how cognitivelly loaded is contemporary world.