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Thank you for taking a look. The passage on the effect in children is a tiny part of the whole work. From the introduction: COVID-19 may affect the central ne
by AnthonBerg 4y ago
Thank you for taking a look.
The passage on the effect in children is a tiny part of the whole work. From the introduction:
COVID-19 may affect the central nervous system in (at least) six main ways (Figure 1). First, the immune response to SARS-CoV-2 in the respiratory system may cause neuroinflammation - increasing
cytokines, chemokines and immune cell trafficking in the brain and inducing reactive states of resident microglia and other immune cells in the brain and brain borders. Second, SARS-CoV-2 rarely may directly infect the nervous system. Third, SARS-CoV-2 may evoke an autoimmune response against the nervous system. Fourth, reactivation of latent herpesviruses like Epstein-Barr virus may trigger neuropathology. Fifth, cerebrovascular and thrombotic disease may disrupt blood flow, disrupt blood-brain-barrier function, and contribute to further neuroinflammation and/or ischemia of neural cells. Lastly, pulmonary and multiorgan dysfunction occurring in severe COVID can cause hypoxemia, hypotension and metabolic disturbances that can negatively affect neural cells. It is important to recognize that these mechanisms of nervous system injury are not mutually exclusive, and a combination of mechanisms may occur in some individuals, with varying frequency and timing.
It has been shown that there are many markers for Long COVID, many of which present as neurological and cognitive issues. Two markers have been shown to be reliable and consistent: Patient reports – and unusually low cortisol levels. The other markers are things such as elevated inflammatory cytokines. Fear and hypochondria and provider nudging do not manifest in those ways. Also: Provider nudging? I have heard of nothing but universal and unscientific dismissal of anything COVID-related when people go to health providers for long-term issues. I don’t think that’s it.
I can’t see how this could be anything less than real, and how children could possibly be exempt from the effects. And we aren’t looking because we think we know it’s nothing.