3 ms·
> Incidentally, these protections exist because of several breakdowns in drug safety in the past, notably Elixir sulfanilamide and Thalidomide. Those protectio
by naasking 4y ago
> Incidentally, these protections exist because of several breakdowns in drug safety in the past, notably Elixir sulfanilamide and Thalidomide.
Those protections are immaterial when the patient is going to die anyway.
- s1artibartfast 4y agoWhich is why the FDA allows it for patients who will have consumed the mushrooms. The paperwork is to show the patient is going to die anyways, and doesnt just have a trivial problem.
- naasking 4y agoI think you're dramatically underselling how complicated and slow this "paperwork" really is. People on their death bed don't have the luxury of bureaucratic approval processes.
- s1artibartfast 4y agoI understand full well how complicated it is. Speed is the challenge, not the lack of a process for this type of situation. Unfortunately, it is a hard one.
- oldgradstudent 4y ago> Those protections are immaterial when the patient is going to die anyway. Only 40% are going to die or require a liver transplant. There is no a-priori reason to assume it won't make things even worse. We have the recent experience of the early months of Covid. In retrospect, it is quite evident that over treatment, especially aggressive intubation and experimental drugs, caused more harm than good. The question is always whether the proposed treatment is safe and effective. Safety, of course, should be relative to the condition being treated.
- naasking 4y ago> The question is always whether the proposed treatment is safe and effective. Safety, of course, should be relative to the condition being treated. Right, which is why the doctors actually treating the patient should be free to make judgment calls without a bureaucrat looking over their shoulder.