3 ms·
> despite its several beneficial effects on the liver, silibinin and all the other compounds found in silymarin, especially silychristin seem to act as potent d
by rex_lupi 4y ago
> despite its several beneficial effects on the liver, silibinin and all the other compounds found in silymarin, especially silychristin seem to act as potent disruptors of the thyroid system by blocking the MCT8 transporter. The long term intake of silymarin can lead to some form of thyroid disease and if taken during pregnancy, silymarin can cause the development of the Allan–Herndon–Dudley syndrome. Although this information is not being taken into consideration by all regulatory bodies, several studies now consider silymarin and especially silychristin to be important inhibitors of the MCT8 transporter and a potential disruptor of the thyroid hormone functions. (From Wikipedia)
I guess emergency use would still be okay?
- deleted 4y ago[deleted]
- scotty79 4y agoThe funny thing is that 100 mg of Silybi mariani fructus extactum siccum is OTC in Poland used for liver problems that people might have after ingesting a heavy meal. And it's been for decades without any safety issues. Granted that in cases of mushroom poisoning it's given only in hospital setting probably through IV, probably in much higher doses. But those people would die without it. Any reasonable safety profile of this drug is better than safety profile of untreated deathcap poisoning.