5 ms·
I'll offer 100-1 odds that this never turns into a human treatment.
by ProjectArcturis 4y ago
I'll offer 100-1 odds that this never turns into a human treatment.
- computerphage 4y agoI'll take the bet. I pay you when it "never" does, and you pay me if it ever does. How does $1 and $100 sound?
- ProjectArcturis 4y agoEngineers are the worst.
- qart 4y agoThe bet might work in your favor. Lots of candiate drugs are discarded for reasons like... having harmful side-effects, being found useless, etc.
- computerphage 4y agoJust because something is dismissed today as a promising candidate doesn't prove it'll never be used for something else in the far future. Many toxic drugs later found use in chemotherapy for cancer; it was suddenly good they were toxic
- RichardCNormos 4y agoI, too, keep my specifics in the pedantry.
- deleted 4y ago[deleted]
- deleted 4y ago[deleted]
- gthippo 4y agoISRIB is licensed by Calico which recently initiated phase I trials for its use in ALS (https://www.massgeneral.org/news/press-release/investigational-drug-initiates-design-phase-for-healey-als-trial https://www.massgeneral.org/news/press-release/investigation...)
- dang 4y ago"Please don't post shallow dismissals, especially of other people's work. A good critical comment teaches us something." https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
- minifridge 4y agoISRIB has toxic effects on the liver, afaik from presentations i have seen. So yeah, unlikely it is going to pass any clinical trial
- minifridge 4y agoWrong, this info I posted is innacurate