Regarding the deuterated version, it's actually possible it would have very different pharmacokinetics to normal ethanol. The first step in metabolism involves

Regarding the deuterated version, it's actually possible it would have very different pharmacokinetics to normal ethanol. The first step in metabolism involves breaking the -O-H bond to create the =O aldehyde, so replacing that with a heaver -O-D would have a kinetic effect. For example, here's a Derek Lowe article about deuterated drugs (not ethanol): - "So a well placed deuterium (or two, or three) can actually have a significant effect on how long a drug will circulate in the bloodstream, by slowing down the liver's clearance mechanism." https://www.science.org/content/blog-post/first-deuterated-drug-arrives https://www.science.org/content/blog-post/first-deuterated-d... ("The First Deuterated Drug Arrives")