I've actually been taking pramipexole for almost two years now for depression which mostly didn't blink for anything else in the past. I certainly do behave di

I've actually been taking pramipexole for almost two years now for depression which mostly didn't blink for anything else in the past. I certainly do behave differently while on it, but not in a way that I think anyone who knew me would claim is inconsistent with my prior personality or behavior, just...less likely to fall into the inertial well that is depression stifling your actions. A strange anecdote, though - my doctor told me when I was tapering up on it "okay, for some medications they tell you you might feel ill taking it initially, but no, for this, I am going to promise you, you will feel sick, and how well you can tolerate feeling sick is going to be the limiter on how fast we taper this", and he was correct, though it was never that bad during the initial taper up, just mild discomfort... ...then one day, the pharmacy gave me 1x1mg pills instead of 4x0.25mg pills, from the same manufacturer, and suddenly I had horrific nausea if I was in anything moving faster than a brisk walk for hours after taking it, and it went away when I went back to the 4x0.25mg. Which was wild, as I've never had motion sickness from anything before. (It's also twice a day because the half-life is real short now, which is annoying, but c'est la vie.) Feel free to ask anything that comes to mind about it, if anecdata interests you.