For an extreme case, I have a large supplementary information document for a paper, of around 175 pages, that takes, if I recall correctly, around 10 minutes to

For an extreme case, I have a large supplementary information document for a paper, of around 175 pages, that takes, if I recall correctly, around 10 minutes to compile on a modern machine. Working on it was frustrating enough that we had methods for compiling small portions we were working on at a given moment, and often used draft mode for the full document. However, this was for a document that, before post-processing, results in a 375 MB PDF, with thousands of included images and PDFs. It has never been that annoying for any normal document I've worked on. The major source of frustration was that there is no partial rebuilding of the document in LaTeX: fixing one word on one page, even if it did not result in any change on the other pages, would require multiple (because of references) compilations of the entire, enormous document, even just to get some sense of what the resulting document would look like. This is a problem that is somewhat unique to LaTeX, I think.