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You do not understand how these drugs work. MDMA is rather similar to certain SSRI in action, if stronger and shorter lived. Which she was already on. Heroinist

You do not understand how these drugs work. MDMA is rather similar to certain SSRI in action, if stronger and shorter lived. Which she was already on. Heroinists with depression tend to shoot a final overdose. The remaining thing to try would be hallucinogens. LSD, psylocibin or perhaps ibogaine. These are different and unpredictable enough to maybe work. And this is a case where, since it is otherwise bad enough, even electroshock therapy could be of value. Since these are way past typical options and probably now banned, they would require special handling. (Assuming VR therapy and standard CBT have been exhausted. And TMS showed no improvement.)

bergenty 4y ago
You’re never going to be able to recreate the combination of factors it takes to get out of depression in a lab. She could have taken some ecstasy, gone to a rave, met someone and completely changed the trajectory of her life. Same with speed- become temporarily manic and do something completely different. Most heroin addicts die from an overdose, you’re underestimating how much an addict looks forward to their next fix, nothing else matters. I’ve seen this anecdotally many times though anecdotal experiences only hold so much weight. At the end of the day what did she have to lose if she was going to be euthanized anyways. People take drugs to deal with problems and this is a problem. Hell, give her a huge dose of ketamine and put her into a massive k hole, people with depression respond fantastically to that. I would never give hallucinogens to a depressed person, that could be enough hell to break someone’s mind permanently.
- slibhb 4y ago
  > I would never give hallucinogens to a depressed person, that could be enough hell to break someone’s mind permanently. If the other option is killing them, hallucinogens start to look a lot more reasonable
  - jquery 4y ago
    This sounds extremely foolish to me. There are fates much worse than death and that’s one way to flirt with them.

bergenty 4y ago

You’re never going to be able to recreate the combination of factors it takes to get out of depression in a lab. She could have taken some ecstasy, gone to a rave, met someone and completely changed the trajectory of her life. Same with speed- become temporarily manic and do something completely different. Most heroin addicts die from an overdose, you’re underestimating how much an addict looks forward to their next fix, nothing else matters. I’ve seen this anecdotally many times though anecdotal experiences only hold so much weight. At the end of the day what did she have to lose if she was going to be euthanized anyways. People take drugs to deal with problems and this is a problem. Hell, give her a huge dose of ketamine and put her into a massive k hole, people with depression respond fantastically to that. I would never give hallucinogens to a depressed person, that could be enough hell to break someone’s mind permanently.

slibhb 4y ago
> I would never give hallucinogens to a depressed person, that could be enough hell to break someone’s mind permanently. If the other option is killing them, hallucinogens start to look a lot more reasonable
- jquery 4y ago
  This sounds extremely foolish to me. There are fates much worse than death and that’s one way to flirt with them.