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The head twitch test is used to determine whether a substance activates 5HT2A in the same way psychedelics do. The forced swim test is used in animal models of
by heavyset_go 4y ago
The head twitch test is used to determine whether a substance activates 5HT2A in the same way psychedelics do.
The forced swim test is used in animal models of depression: https://en.m.wikipedia.org/wiki/Behavioural_despair_test https://en.m.wikipedia.org/wiki/Behavioural_despair_test
I'm a layman, I don't know what the scientific basis is for using the test to model depression. I personally find it pretty cruel.