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>but rather ineffective in general. Study with 22 people with major depression: "Treatment with both omega-3s was associated with a significant improvement in

>but rather ineffective in general. Study with 22 people with major depression: "Treatment with both omega-3s was associated with a significant improvement in depression, with an average 64% drop in symptoms for the EPA group and 71% in the DHA group." https://www.webmd.com/depression/news/20210618/fish-oil-supplements-may-help-fight-depression#:~:text=Byproducts%20of%20EPA%20and%20DHA,71%25%20in%20the%20DHA%20group https://www.webmd.com/depression/news/20210618/fish-oil-supp....

guerrilla 4y ago
> Study with 22 people i.e. worthless. DHA is being studied and has massive effects on inflammation but the science is definitely not there for depression. You need to adjust your epistemology if you are making decisions based on tiny studies like that.
- hallway_monitor 4y ago
  Seems like 22 subjects is better than zero. One is better than zero so if it worked for one person that's probably worth trying for a second. I hate how people act like you can't try anything until it has had a study with thousands of people over years. Sure, that increases confidence but in most cases the study doesn't invent a treatment, it just adds trust in the effectiveness.
  - guerrilla 4y ago
    No, that's not how it works at all or else we should also recommend fairy crystals at the same time. Anyway, people do try it. That's the point. It's common practice and it's known to not work for most people with severe depression. It's only a matter of time that we have strong meta-meta studies showing that definitively. For now, here's a Cochrane meta-study that reviews 35 studies [1]. 1. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004692.pub5/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...
- Silverback_VII 4y ago
  >i.e. worthless Certainly not and considering the almost non-existent side effects, it is at least worth a try since it looks very promising. You are right that it is a tiny study but it doesn't mean that it has no value. I have to say that I know people like you very well, I almost can hear the "go see a therapist and take your meds" or better "don't try and certainly don't think you can solve this on your own". A positive force first and foremost acknowledge people's potential and doesn't put roadblocks everywhere.

guerrilla 4y ago

> Study with 22 people i.e. worthless. DHA is being studied and has massive effects on inflammation but the science is definitely not there for depression. You need to adjust your epistemology if you are making decisions based on tiny studies like that.

hallway_monitor 4y ago
Seems like 22 subjects is better than zero. One is better than zero so if it worked for one person that's probably worth trying for a second. I hate how people act like you can't try anything until it has had a study with thousands of people over years. Sure, that increases confidence but in most cases the study doesn't invent a treatment, it just adds trust in the effectiveness.
- guerrilla 4y ago
  No, that's not how it works at all or else we should also recommend fairy crystals at the same time. Anyway, people do try it. That's the point. It's common practice and it's known to not work for most people with severe depression. It's only a matter of time that we have strong meta-meta studies showing that definitively. For now, here's a Cochrane meta-study that reviews 35 studies [1]. 1. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004692.pub5/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...
Silverback_VII 4y ago
>i.e. worthless Certainly not and considering the almost non-existent side effects, it is at least worth a try since it looks very promising. You are right that it is a tiny study but it doesn't mean that it has no value. I have to say that I know people like you very well, I almost can hear the "go see a therapist and take your meds" or better "don't try and certainly don't think you can solve this on your own". A positive force first and foremost acknowledge people's potential and doesn't put roadblocks everywhere.