Eh, I wouldn't call the mental effects of NBOMe's objectively worse than say LSD -- just different Now, the body load/vasoconstriction + other physical effects

Eh, I wouldn't call the mental effects of NBOMe's objectively worse than say LSD -- just different Now, the body load/vasoconstriction + other physical effects, definitely. You can always tell the NBOMe is kicking in when you get shuttery cold from vasoconstriction and have a weird motor rigidity. Also FWIW, there are more potent agonists than NBOMe. I know of at least one discovered by Nichols' lab that they refused to publish for fear of use as an aerosolized bio-weapon.