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Or tripping? I think that we can ascertain some things from their physiological responses, eg fear, anxiety and being content. Obviously there’s a lot we don’t
by Synaesthesia 4y ago
Or tripping? I think that we can ascertain some things from their physiological responses, eg fear, anxiety and being content. Obviously there’s a lot we don’t know about their internal state. Psychedelics really need to be tested on humans.
- krispyfi 4y agohttps://en.m.wikipedia.org/wiki/Head-twitch_response https://en.m.wikipedia.org/wiki/Head-twitch_response
- YorkshireSeason 4y agoWhat scientifically credible, i.e. at least stably reproducible, connection does the head twitch response in mice have to do with depression in humans?
- heavyset_go 4y agoThe head twitch test is used to determine whether a substance activates 5HT2A in the same way psychedelics do. The forced swim test is used in animal models of depression: https://en.m.wikipedia.org/wiki/Behavioural_despair_test https://en.m.wikipedia.org/wiki/Behavioural_despair_test I'm a layman, I don't know what the scientific basis is for using the test to model depression. I personally find it pretty cruel.