I’m surprised no one has mentioned this so, I’ve built a very easy to use and modify stack based on PostgreSQL (or SQLite) depending on needs fed into a Flask

I’m surprised no one has mentioned this so, I’ve built a very easy to use and modify stack based on PostgreSQL (or SQLite) depending on needs fed into a Flask Python BE. You can ORM it with SQLAlchemy if you like or just run raw queries. You’re running that basically out of as little as one file and you have your API and DB. At that point you’re free to decide how you want to run your client side, I tend to start with HTML and avoid JS until it’s necessary, then convert where relevant into React. As other posters have mentioned Tailwind is awesome for avoiding writing custom css, there’s a class for literally everything. Clear separation between your API and your FE pays off down the line.