It sounds like the question they still need to answer is if this effect continues indefinitely, or if it is a one time effect. Across a 10 year disease progress

It sounds like the question they still need to answer is if this effect continues indefinitely, or if it is a one time effect. Across a 10 year disease progression this could slow it down by 2.5 years. I might make that trade off, at least in the early stages of the disease. Not sure I would want to slow things down in the later stages though. At that point just get it over with. It is also not clear from the press release what the response distribution looks like. If some people respond really well and others do not (but it averages out to 27%), maybe Alzheimers treatment starts to look a bit more like cancer. Where you try a few things and hope something sticks. My hunch is that is probably where we are headed, but I am not an expert in this stuff.