> It is not clear to me why we should "ignore anyone" who makes this comparison? I said that we should ignore people trying to compare this drug to recreationa

> It is not clear to me why we should "ignore anyone" who makes this comparison? I said that we should ignore people trying to compare this drug to recreational use. It's likely that NMDA is in play and I'm not suggesting otherwise. I wanted to highlight that DXM has significant affinities for other targets like the serotonin transporter that could also explain the efficacy, so it's a mistake to focus on one receptor as the single answer.