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I understand why you think that, and it's true enough for most classical vaccines. But, the mRNA vaccines are different in at least five ways from the actual vi
by origin_path 4y ago
I understand why you think that, and it's true enough for most classical vaccines. But, the mRNA vaccines are different in at least five ways from the actual virus:
1. The spike protein it creates is structurally slightly different; they edited its structure to stop it collapsing in the absence of the rest of the virus.
2. The mRNA that codes for the spike is 'optimized' in ways nature either can't or won't do. In theory the optimized versions and viral versions are equivalent except for potency.
3. The mRNA is obfuscated to hide it from the immune system, which would otherwise immediately destroy it as being too dangerous to allow. This involves pseudouridine substitutions. It's a part of what makes the tech experimental.
4. The mRNA is protected by "lipid nanoparticles". This tech is totally different to what the virus does, and has caused unexpected toxicity problems in the past. In fact it's why mRNA based drugs never launched and why the COVID vaccines were the first outing for the tech despite it being under development for many years. They thought the toxicity wouldn't matter because the nanoparticles only become problematic on repeat dosings which, as everyone knows, vaccines don't require (doh).
5. The vaccine enters the body via a very different pathway, one which is far more likely to result in accidental injection straight into the bloodstream. For normal viral replication it often gets stuck in the nose, mouth, throat or lungs and can't reach e.g. the heart or the reproductive organs.