Assuming your workload can run on ARM, you should think of it as a different CPU generation or AMD vs Intel. For some applications, you might care about speed.

Assuming your workload can run on ARM, you should think of it as a different CPU generation or AMD vs Intel. For some applications, you might care about speed. Others, +/- 5ms isn't an issue. Then you see how much throughput each supports. Finally, you go through the total cost math. It's hard to make a blanket statement about which will be better for your usecase.