That depends on where you live in the EU, but it is something you need to be aware of. Applying for a US job and work remote could be a legal and administrative

That depends on where you live in the EU, but it is something you need to be aware of. Applying for a US job and work remote could be a legal and administrative nightmare for an employer, especially if you're the only one not in the US. A workaround is to have an employer of record in your country, who will be doing the actual hiring, and you effectively act as a contractor or consultant. It's not a fantastic solution, but it does work. Timezones are a major hassle. You will end up with a lot of weird late afternoon, early evening meetings, which isn't great for family life. That might not matter if you're end up in the top 3% earners and your partner doesn't need to work as a result. For some countries also be aware of things like on call. A US employer might not be ready to deal with the legal requirements in your country.