4 ms·

Using old-school lye will get rid of PFAS on your clothes. I wonder if that was considered during these tests. https://www.nbcnews.com/health/health-news/new-w

• PaulHoule 4y ago
  + DMSO and high temperatures. Lye will probably wreck your clothes too. Last time I played around with DMSO I made an ibuprofen ointment similar to the diclofenac ointments there were expensive and prescription-required back then. I'd apply some to my skin and it would absorb very quick and I'd get digestive upset even more quickly than if I took ibuprofen pills so it was a success and a failure at the same time.
  • pacaro 4y ago
    Memories of my first job, between high school and university, I worked as a technician in a pharmaceutical formulation lab. Our main project was a topical Diclofenac preparation. We worked on both creams and an aerosol (post foam) dispenser. Balancing solvents, waxes, surfactants, and propellant (also a solvent) to create a foam that dissolves at the right speed was an interesting challenge. I have no idea whether our product ever went to market as I moved on to university and other things. IIRC we explicitly didn't use DMSO because of concerns with toxicity, and just accepted that the absorbance rate was astonishingly low, clinical trials suggested that it took 24-48 hours for the active ingredient to be detected in the blood. My recollections are hazy, this was over 30 years ago